Most Important MCAT Topics From Biology Part 1 & Chapter 2 Part 6

Most Important MCAT Topics From Biology Part 1 & Chapter 2 Part 6

SECONDARY STRUCTURE:

Note:
         Important MCQS are highlighted with Blue color.

*Polypeptide chain in protein molecule coil into HELIX.

*One of common Secondary Structure is @-Helix.

*It Involves SPIRAL Formation.

*@-Helix is uniform geometric structure with 3.6 amino-  acids in each turn of the Helix.

*Helical Structure has H-Bonding among Amino-Acids

*Beta-Plated Sheet is formed by folding back of polypeptide.

EXAMPLE:
                   Myosin & Silk etc.

TERTIARY STRUCTURE:

*Globular Structure is Formed in Tertiary structure.

 *Globular Structure is maintained by Three Types Of Bonds,
    (1)= Ionic  (2)= Hydrogen  (3)= Disulphide -S-S-

 EXAMPLE:
IN AQOUS ENVIRONMENT,
                  The Most Stable Tertiary Structure Conformation is that in which  HYDROPHOBIC AMINO ACIDS are buried inside while HYDROPHILIC AMINO ACIDS are on surface of molecule.
e.g: Enzymes.

QUATERNARY STRUCTURE:

*Highly COMPLEX Protein

 *Held Together By HYDROPHOBIC INTERACTIONS, Hydrogen Bonding , Ionic Bonding .
 EXAMPLE:
                  Haemoglobin.


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